Recombinant CD80 (Galiximab Biosimilar) anticorps

N° du produit ABIN7795110

L’anticorps Humanized Monoclonal anti-CD80 (Galiximab Biosimilar) a été validé pour FACS et in vivo. Il convient pour détecter CD80 (Galiximab Biosimilar) dans des échantillons de Humain.

Aperçu rapide pour Recombinant CD80 (Galiximab Biosimilar) anticorps (ABIN7795110)

Antigène: CD80 (Galiximab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Humanized

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 (Galiximab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité: Research Grade

Détail du produit anti-CD80 (Galiximab Biosimilar) anticorps

Expression System: Mammalian cells

Fonction: Galiximab Biosimilar, CD80 Monoclonal Antibody

Attributs du produit: A humanized IgG1 monoclonal antibody directed against CD80, the natural ligand for the T-cell antigen CD28 which mediates T-cell and B-cell adhesion. Galiximab binds to CD80 expressed on the cell surfaces of follicular lymphomas, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC). CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes and is often expressed at low levels on the surfaces of follicular lymphoma cells and other lymphoid malignancies. Galiximab, an IgG(1) anti-CD80 antibody, binds to CD80, a costimulatory molecule involved in T-cell activation. Reduction in lesional, activated T cells induces improvement in psoriatic plaques.

Purification: Protein A or G affinity column

Pureté: >95 % by reducing SDS-PAGE

niveau d'endotoxine: < 1 EU per 1 mg of the protein by the LAL method

Immunogène: Human CD80

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: > 3 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Détails sur CD80 (Galiximab Biosimilar)

Antigène: CD80 (Galiximab Biosimilar)

Autre désignation: Galiximab Biosimilar

Classe de substances: Biosimilar